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Chemical Compound Review:

CHEMBL279865 (1-methyl-4-phenyl-4- piperidyl) propanoate

Synonyms: SureCN614226, AG-D-63871, IK 13, AC1L1VIT, CTK4B7313, ...

Pritzker, D. et al., Johannessen, J.N. et al.

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High impact information on Desmethylprodine

Only 1-methyl-4-phenyl-4-propionoxypiperidine (MPPP) and 1-[2-phenylethyl]-4-phenyl-4-acetoxypiperidine (PEPAP) interacted significantly (Ki 1.6 microM and 0.3 microM, respectively) [1].
Chemical analysis has revealed the ingredients to be two related compounds 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 1-methyl-4-phenyl-4-propionoxypiperidine (MPPP) [2].

References

Designer drugs that are potent inhibitors of CYP2D6. Pritzker, D., Kanungo, A., Kilicarslan, T., Tyndale, R.F., Sellers, E.M. Journal of clinical psychopharmacology. (2002) [Pubmed]
Assessment of the opiate properties of two constituents of a toxic illicit drug mixture. Johannessen, J.N., Markey, S.P. Drug and alcohol dependence. (1984) [Pubmed]

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