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Chemical Compound Review

SureCN3036462     (Z)-7-[(1R,2S,3R,5R)-5- chloro-2-[(E,3S)-3...

Synonyms: AC1O5QVE, ZK-110 841, ZK 110841, 105595-17-3
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High impact information on ZK 110841

  • BW 245C, an agonist for PGD2 receptors (DP receptors), but not another DP receptor agonist (ZK 110841) blocked the allodynia similarly [1].
  • ZK 110 841 is a chemically stable crystalline substance, which is orally active and which might thus turn out to be an interesting tool for the study of PGD2-receptor interactions [2].


  1. Prostaglandin D2 inhibits prostaglandin E2-induced allodynia in conscious mice. Minami, T., Okuda-Ashitaka, E., Mori, H., Ito, S., Hayaishi, O. J. Pharmacol. Exp. Ther. (1996) [Pubmed]
  2. Stable 9 beta- or 11 alpha-halogen-15-cyclohexyl-prostaglandins with high affinity to the PGD2-receptor. Thierauch, K.H., Stürzebecher, C.S., Schillinger, E., Rehwinkel, H., Radüchel, B., Skuballa, W., Vorbrüggen, H. Prostaglandins (1988) [Pubmed]
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