Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

CHEMBL21409 3-[(3E,7E,11E,15E)-18-(3,3- dimethyloxiran...

Synonyms: CHEBI:126786, AC1O5UJW, 14031-18-6, 14031-39-1, 26955-87-3, ...

Viola, F. et al.

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High impact information on Squalene-2,3-22,23-dioxide

In the presence of 17, 19 and 21, only the intermediate metabolites 2,3-oxidosqualene and 2,3,22,23-dioxidosqualene accumulated, demonstrating a very specific inhibition of OSC [1].

References

Inhibition of 2,3-oxidosqualene cyclase and sterol biosynthesis by 10- and 19-azasqualene derivatives. Viola, F., Brusa, P., Balliano, G., Ceruti, M., Boutaud, O., Schuber, F., Cattel, L. Biochem. Pharmacol. (1995) [Pubmed]

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