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Chemical Compound Review

Sdz-nim-811     (3S,6S,9S,12R,15S,18S,21S,24S, 30S,33S)-24...

Synonyms: NIM-811, NIM811, CHEMBL1688529, NIM 811, CHEBI:1176129, ...
 
 
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High impact information on Sdz nim 811

  • NIM811 inhibition of apoptosis was equipotent with CsA except at higher concentrations: CsA lost efficacy but NIM 811 did not [1].

References

  1. Inhibition of the mitochondrial permeability transition by the nonimmunosuppressive cyclosporin derivative NIM811. Waldmeier, P.C., Feldtrauer, J.J., Qian, T., Lemasters, J.J. Mol. Pharmacol. (2002) [Pubmed]
 
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