Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

PubChem21431 2,6-dihydroxybenzoic acid

Synonyms: CHEMBL454808, SureCN224031, ACMC-1CRQN, AG-E-99536, AG-L-22854, ...

Hinz, B. et al., Ishii, Y. et al.

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Disease relevance of gamma-Resorcylic acid

Reversible and nonoxidative gamma-resorcylic acid decarboxylase: characterization and gene cloning of a novel enzyme catalyzing carboxylation of resorcinol, 1,3-dihydroxybenzene, from Rhizobium radiobacter [1].

High impact information on gamma-Resorcylic acid

In contrast, gamma-resorcylic acid (2,6-dihydroxybenzoic acid) as well as unconjugated coenzyme A failed to affect prostanoid synthesis, implying that the para-substitution of hydroxy groups and the activated coenzyme A thioester are important for COX-2 inhibition [2].

References

Reversible and nonoxidative gamma-resorcylic acid decarboxylase: characterization and gene cloning of a novel enzyme catalyzing carboxylation of resorcinol, 1,3-dihydroxybenzene, from Rhizobium radiobacter. Ishii, Y., Narimatsu, Y., Iwasaki, Y., Arai, N., Kino, K., Kirimura, K. Biochem. Biophys. Res. Commun. (2004) [Pubmed]
Salicylate metabolites inhibit cyclooxygenase-2-dependent prostaglandin E(2) synthesis in murine macrophages. Hinz, B., Kraus, V., Pahl, A., Brune, K. Biochem. Biophys. Res. Commun. (2000) [Pubmed]

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