Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AG-F-85987 3-hydroxydodecanoic acid

Synonyms: AG-L-65463, CHEBI:36206, H3398_SIGMA, HMDB00387, AC1Q5VDT, ...

Parlesak, A. et al., Segre, A. et al.

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High impact information on beta-Hydroxylauric acid

Its amino acid sequence is Ser-Ser-Dab-Dab-Arg-Phe-Dhb-4(Cl)Thr-3(OH)Asp with the beta-carboxy group of the C-terminal residue closing a macrocyclic ring on the OH group of the N-terminal Ser, which in turn is N-acylated by 3-hydroxydodecanoic acid [1].
The determination of lipid A was based on the quantitative measurement of beta-hydroxymyristic acid and beta-hydroxylauric acid by reversed-phase HPLC. beta-Hydroxy acids were liberated from ester and amide linkages in endotoxins by acid catalyzed methanolysis [2].

References

The structure of syringomycins A1, E and G. Segre, A., Bachmann, R.C., Ballio, A., Bossa, F., Grgurina, I., Iacobellis, N.S., Marino, G., Pucci, P., Simmaco, M., Takemoto, J.Y. FEBS Lett. (1989) [Pubmed]
Lipopolysaccharide determination by reversed-phase high-performance liquid chromatography after fluorescence labeling. Parlesak, A., Bode, C. Journal of chromatography. A. (1995) [Pubmed]

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