Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AG-E-37801 6-amino-7-chloro-quinoline- 5,8-dione

Synonyms: CHEMBL1098773, SureCN1612515, NSC-81056, NSC-84998, AC1L3WRU, ...

Ogilvie, A. et al., Ogilvie, A. et al.

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Disease relevance of NSC84998

5. It is concluded that the bacteriostatic effect of 5,8-dioxo-6-amino-7-chloroquinoline on E. coli is caused by an apparent intracellular amino acid starvation [1].

High impact information on NSC84998

Inhibition of leucyl-tRNA synthetase in Escherichia coli by the cytostatic 5,8-dioxo-6-amino-7-chloroquinoline [2].
Quinone induced stringent control. Accumulation of ppGpp and inhibition of RNA synthesis in stringent Escherichia coli by 5,8-dioxo-6-amino-7-chloroquinoline [1].

References

Quinone induced stringent control. Accumulation of ppGpp and inhibition of RNA synthesis in stringent Escherichia coli by 5,8-dioxo-6-amino-7-chloroquinoline. Ogilvie, A., Lämmerman, M., Wiebauer, K., Kersten, W. Biochim. Biophys. Acta (1975) [Pubmed]
Inhibition of leucyl-tRNA synthetase in Escherichia coli by the cytostatic 5,8-dioxo-6-amino-7-chloroquinoline. Ogilvie, A., Wiebauer, K., Spitzbarth, P., Kersten, W. Biochim. Biophys. Acta (1975) [Pubmed]

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