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Gene Review

aphA  -  acid phosphatase/phosphotransferase

Escherichia coli CFT073

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Disease relevance of aphA

  • The Escherichia coli gene aphA codes for a periplasmic acid phosphatase called AphA, belonging to class B bacterial phosphatases, which is part of the DDDD superfamily of phosphohydrolases [1].


  1. A structure-based proposal for the catalytic mechanism of the bacterial acid phosphatase AphA belonging to the DDDD superfamily of phosphohydrolases. Calderone, V., Forleo, C., Benvenuti, M., Thaller, M.C., Rossolini, G.M., Mangani, S. J. Mol. Biol. (2006) [Pubmed]
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