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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Gbf1  -  golgi-specific brefeldin A-resistance...

Mus musculus

Synonyms: 1700083E03Rik, AI035702, AW049900, mKIAA0248
 
 
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High impact information on Gbf1

  • A recent report described a deletion in the intergenic region between Gbf1 and Pitx3 as the possible ak mutation [1].
  • Pitx3 transcript levels are severely reduced in ak/ak mice from E11.5 to newborn (5 +/- 1% of the wildtype levels at E13.5), while an involvement of the flanking Gbf1 and Cig30 genes in the aberrant lens development is highly unlikely based on expression analysis [1].

References

  1. A double-deletion mutation in the Pitx3 gene causes arrested lens development in aphakia mice. Rieger, D.K., Reichenberger, E., McLean, W., Sidow, A., Olsen, B.R. Genomics (2001) [Pubmed]
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