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Gene Review

Pbr  -  resistance to Paracoccidioides brasiliensis

Mus musculus

 
 
 
 
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High impact information on Pbr

  • Analysis of susceptible and resistant parental strains and of F1, F2, and backcross mice showed that the resistance to P. brasiliensis seems to be controlled genetically by a single dominant gene, which we designated the Pbr locus [1].
  • The Pbr gene is not linked to H-2, Hc, and albino genes [1].

References

  1. Resistance to Paracoccidioides brasiliensis in mice is controlled by a single dominant autosomal gene. Calich, V.L., Burger, E., Kashino, S.S., Fazioli, R.A., Singer-Vermes, L.M. Infect. Immun. (1987) [Pubmed]
 
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