The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Gene Review

Tria1  -  T cell receptor induced activation 1

Mus musculus


Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance

T lymphocytes with their multiple regulatory and effector functions are one of the cornestones of vertebrate immune systems. They participate in localization and removal of virally infected and neoplastic cells, collaborate in stimulating antibody production and macrophage information. Understanding genetic regulation of their functions by loci such as Tria1 is therefore of great importance.



High impact information on Tria1

Locus Tria1 (T cell receptor induced activation 1) that controls proliferation of T lymphocytes stimulated by antiCD3 was mapped on chromosome 11 near to the marker D11Nds9 [1].




  1. Genetic control of T-cell proliferative response in mice linked to chromosomes 11 and 15. Havelková, H., Krulová, M., Kosarová, M., Holán, V., Hart, A.A., Demant, P., Lipoldová, M. Immunogenetics. (1996) [Pubmed]
WikiGenes - Universities