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Gene Review

MJ_0158  -  selenocystein synthase SelA

Methanocaldococcus jannaschii DSM 2661

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Disease relevance of MJ0158

  • However, biochemical analyses demonstrated that MJ0158 lacked affinity for E. coli seryl-tRNA(Sec) or M. jannaschii seryl-tRNA(Sec), and neither substrate was directly converted to selenocysteinyl-tRNA(Sec) by MJ0158 when supplied with selenophosphate [1].


  1. Structural and functional investigation of a putative archaeal selenocysteine synthase. Kaiser, J.T., Gromadski, K., Rother, M., Engelhardt, H., Rodnina, M.V., Wahl, M.C. Biochemistry (2005) [Pubmed]
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