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Gene Review

mCCPH  -  complement control protein homologue

Saimiriine herpesvirus 2

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High impact information on mCCPH

  • The function of CCPH was further defined by showing that the mCCPH and the 5'FLAGmCCPH transfectants inhibited C3 convertase activity and effectively reduced cell surface deposition of the activated complement component, C3d [1].


  1. The complement control protein homolog of herpesvirus saimiri regulates serum complement by inhibiting C3 convertase activity. Fodor, W.L., Rollins, S.A., Bianco-Caron, S., Rother, R.P., Guilmette, E.R., Burton, W.V., Albrecht, J.C., Fleckenstein, B., Squinto, S.P. J. Virol. (1995) [Pubmed]
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