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Gene Review

H2-DMb1  -  histocompatibility 2, class II, locus Mb1

Mus musculus

Synonyms: AI385589, Class II histocompatibility antigen, M beta 1 chain, H-2Mb1, H2-M beta 1 chain, H2-M beta1, ...
 
 
 
 
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High impact information on H2-DMb1

  • In contrast to the HLA-DM region in humans, the beta-chain locus is duplicated in mice, with the H2-Mb1 beta-chain distal to H2-Mb2 and the H2-Ma alpha-chain gene [1].

References

  1. H2-Mbeta 1 and H2-Mbeta 2 heterodimers equally promote clip removal in I-A(q) molecules from autoimmune-prone DBA/1 mice. Walter, W., Scheuer, C., Loos, M., Reichert, T.E., Maeurer, M.J. J. Biol. Chem. (2001) [Pubmed]
 
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