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Gene Review

RASEF  -  RAS and EF-hand domain containing

Homo sapiens

Synonyms: FLJ31614, RAB45, Ras and EF-hand domain-containing protein, Ras-related protein Rab-45
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Disease relevance of RASEF

  • Expression of RASEF, a known gene in this region, was examined in tumor tissue from 10 sporadic CMM lesions and was found to be decreased in 70% of these tumors compared with RASEF expression in a human reference RNA pool from 10 different cell types and in 10 breast tumors [1].


  1. Mapping of a novel ocular and cutaneous malignant melanoma susceptibility locus to chromosome 9q21.32. Jönsson, G., Bendahl, P.O., Sandberg, T., Kurbasic, A., Staaf, J., Sunde, L., Crüger, D.G., Ingvar, C., Olsson, H., Borg, A. J. Natl. Cancer Inst. (2005) [Pubmed]
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