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Gene Review

mig-17  -  Protein MIG-17

Caenorhabditis elegans

 
 
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High impact information on mig-17

  • The mig-23 mutation causes defective migration of DTCs and interacts genetically with mig-17 [1].
  • Specific amino acid substitutions in the third EGF-like motif of one of the two isoforms, FBL-1C, which corresponds to mammalian fibulin-1C, suppress mig-17 mutations [2].

References

  1. An NDPase links ADAM protease glycosylation with organ morphogenesis in C. elegans. Nishiwaki, K., Kubota, Y., Chigira, Y., Roy, S.K., Suzuki, M., Schvarzstein, M., Jigami, Y., Hisamoto, N., Matsumoto, K. Nat. Cell Biol. (2004) [Pubmed]
  2. A fibulin-1 homolog interacts with an ADAM protease that controls cell migration in C. elegans. Kubota, Y., Kuroki, R., Nishiwaki, K. Curr. Biol. (2004) [Pubmed]
 
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