Gene Review:
sur-7 - Protein SUR-7
Caenorhabditis elegans
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High impact information on sur-7
- We identified sur-7 by isolating a mutation that suppresses an activated ras allele, and showed that SUR-7 is a divergent member of the cation diffusion facilitator family of heavy metal ion transporters that is probably localized to the endoplosmic recticulum membrane and regulates cellular Zn(2+) concentrations [1].
References
- Modulation of KSR activity in Caenorhabditis elegans by Zn ions, PAR-1 kinase and PP2A phosphatase. Yoder, J.H., Chong, H., Guan, K.L., Han, M. EMBO J. (2004) [Pubmed]
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