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Gene Review

NLRC3  -  NLR family, CARD domain containing 3

Homo sapiens

Synonyms: CARD15-like protein, CLR16.2, Caterpiller protein 16.2, FLJ00348, NOD3, ...
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High impact information on NLRC3

  • The presence of apparent bony fish orthologs of NOD3 and CIITA supported the hypothesis that the origin of these molecules predates the origin of tetrapods, and the presence of avian sequences in both NALP and NOD clusters supported the origin of these subfamilies before the bird-mammal divergence [1].


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