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Gene Review

ZCCHC11  -  zinc finger, CCHC domain containing 11

Homo sapiens

Synonyms: KIAA0191, PAPD3, TUT4, TUTase 4, Terminal uridylyltransferase 4, ...
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High impact information on ZCCHC11

  • Overexpression and knockdown by siRNA indicated that ZCCHC11 functions as a negative regulator of TLR-mediated NF-kappaB activation [1].


  1. A novel Zinc finger protein, ZCCHC11, interacts with TIFA and modulates TLR signaling. Minoda, Y., Saeki, K., Aki, D., Takaki, H., Sanada, T., Koga, K., Kobayashi, T., Takaesu, G., Yoshimura, A. Biochem. Biophys. Res. Commun. (2006) [Pubmed]
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