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Gene Review:

Tcstv3 - 2-cell-stage, variable group, member 3

Mus musculus

Synonyms: clone L3

Lancki, D.W. et al., Hao, L.M. et al.

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High impact information on Tcstv3

Concanavalin A-facilitated cytolysis by T cell clone L3 but not T cell clone B18 was inhibited by antibody 384.5, whereas phytohemagglutinin-facilitated cytolysis by L3 cells was not strongly inhibited [1].

Analytical, diagnostic and therapeutic context of Tcstv3

The alloreactive T cell clone L3 will transfer allograft immunity, and this process is also sensitive to CsA [2].

References

A clone-specific monoclonal antibody that inhibits cytolysis of a cytolytic T cell clone. Lancki, D.W., Lorber, M.I., Loken, M.R., Fitch, F.W. J. Exp. Med. (1983) [Pubmed]
Role of lymphokine in islet allograft rejection. Hao, L.M., Wang, Y., Gill, R.G., La Rosa, F.G., Talmage, D.W., Lafferty, K.J. Transplantation (1990) [Pubmed]

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