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Gene Review

AUTS2  -  autism susceptibility candidate 2

Homo sapiens

Synonyms: Autism susceptibility gene 2 protein, FBRSL2, KIAA0442, MRD26
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High impact information on AUTS2

  • Thus, although it is unlikely that AUTS2 is an autism susceptibility gene for idiopathic autism, it may be the gene responsible for the disorder in the twins studied here [1].
  • AUTS2 is 1.2 Mb and has 19 exons [1].
  • Association analysis with two exonic polymorphic sites and linkage analysis of four dinucleotide repeat markers, two within and two flanking AUTS2, was negative [1].


  1. Identification of a novel gene on chromosome 7q11.2 interrupted by a translocation breakpoint in a pair of autistic twins. Sultana, R., Yu, C.E., Yu, J., Munson, J., Chen, D., Hua, W., Estes, A., Cortes, F., de la Barra, F., Yu, D., Haider, S.T., Trask, B.J., Green, E.D., Raskind, W.H., Disteche, C.M., Wijsman, E., Dawson, G., Storm, D.R., Schellenberg, G.D., Villacres, E.C. Genomics (2002) [Pubmed]
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