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Gene Review

ANKRD17  -  ankyrin repeat domain 17

Homo sapiens

Synonyms: Ankyrin repeat domain-containing protein 17, FLJ22206, GTAR, Gene trap ankyrin repeat protein, KIAA0697, ...
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High impact information on ANKRD17

  • We have used ES cells carrying a gene trap vector insertion (I.114) into an ankyrin repeat-containing gene (Gtar) that we have previously shown provides an exclusive beta-galactosidase marker for the early differentiation of hepatocytes in vivo. beta-Galactosidase-positive cells were differentiated from I.114 ES cells in vitro [1].
  • The most promising candidate for a T-cell epitope is an HLA-B7-binding nonamer peptide derived from the tumor-associated gene NY-BR-16 [2].


  1. Hepatic differentiation of murine embryonic stem cells. Jones, E.A., Tosh, D., Wilson, D.I., Lindsay, S., Forrester, L.M. Exp. Cell Res. (2002) [Pubmed]
  2. Rapid and sensitive identification of major histocompatibility complex class I-associated tumor peptides by Nano-LC MALDI MS/MS. Hofmann, S., Glückmann, M., Kausche, S., Schmidt, A., Corvey, C., Lichtenfels, R., Huber, C., Albrecht, C., Karas, M., Herr, W. Mol. Cell Proteomics (2005) [Pubmed]
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