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Gene Review

Yme1l1  -  YME1-like 1 (S. cerevisiae)

Mus musculus

Synonyms: ATP-dependent metalloprotease FtsH1, ATP-dependent zinc metalloprotease YME1L1, FtsH1, Ftsh, YME1-like protein 1
 
 
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Disease relevance of Yme1l1

  • Streptococcus pneumoniae is an important human pathogen that contains single copies of genes encoding the ClpP and FtsH ATP-dependent proteases but lacks the Lon and HslV proteases [1].

References

  1. Global transcriptional analysis of clpP mutations of type 2 Streptococcus pneumoniae and their effects on physiology and virulence. Robertson, G.T., Ng, W.L., Foley, J., Gilmour, R., Winkler, M.E. J. Bacteriol. (2002) [Pubmed]
 
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