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Gene Review

HOOK2  -  hook microtubule-tethering protein 2

Homo sapiens

Synonyms: HK2, Protein Hook homolog 2, h-hook2, hHK2
 
 
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Disease relevance of HOOK2

  • The sero-positive rates of antibodies against SURF1 (48%), LOC146223 (38%), HOOK2 (14%) and AGENCOURT_7565913 (14%) were significantly higher in esophageal cancer patients than in healthy controls [1].
  • A disease-specific humoral immune response against SURF1, LOC146223, HOOK2 or AGENCOURT_7565913 was observed in most patients with esophageal squamous cell carcinoma [1].

References

  1. Serological identification of tumor antigens of esophageal squamous cell carcinoma. Shimada, H., Nakashima, K., Ochiai, T., Nabeya, Y., Takiguchi, M., Nomura, F., Hiwasa, T. Int. J. Oncol. (2005) [Pubmed]
 
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