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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Ulp1  -  CG12359 gene product from transcript...

Drosophila melanogaster

Synonyms: BcDNA:GH02751, CG12359, DmUlp1, Dmel\CG12359, ulp1
 
 
 
 
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High impact information on Ulp1

  • In the presence of Ulp1, most SUMO conjugates reside in the nucleus [1].
  • Studies of a Ulp1-GFP fusion protein suggest that Ulp1 localizes to the nucleoplasmic face of the nuclear pore complex [1].
  • Ulp1 normally serves to prevent the accumulation of SUMO-conjugated forms of a number of proteins, including the aminoacyl-tRNA synthetase EPRS [1].

References

  1. Drosophila Ulp1, a nuclear pore-associated SUMO protease, prevents accumulation of cytoplasmic SUMO conjugates. Smith, M., Bhaskar, V., Fernandez, J., Courey, A.J. J. Biol. Chem. (2004) [Pubmed]
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