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Gene Review:

bopA - BopA protein

Burkholderia pseudomallei 1710b

Stevens, M.P. et al.

Stevens, Haque, Atkins, Hill, Wood, Easton, Nelson, Underwood-Fowler, Titball, Bancroft, Galyov,

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High impact information on bopA

B. pseudomallei mutants lacking either the type III secreted guanine nucleotide exchange factor BopE or the putative effectors BopA or BopB exhibited varying degrees of attenuation, with mutations in bopA and bopB causing a significant delay in median time to death [1].

References

Attenuated virulence and protective efficacy of a Burkholderia pseudomallei bsa type III secretion mutant in murine models of melioidosis. Stevens, M.P., Haque, A., Atkins, T., Hill, J., Wood, M.W., Easton, A., Nelson, M., Underwood-Fowler, C., Titball, R.W., Bancroft, G.J., Galyov, E.E. Microbiology (Reading, Engl.) (2004) [Pubmed]

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