Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

olf186-F - CG11430 gene product from transcript...

Drosophila melanogaster

Synonyms: BcDNA:LD03241, CG11430, CRACM1, Calcium release-activated calcium channel protein 1, Dmel\CG11430, ...

Zhang, S.L. et al.

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High impact information on olf186-F

Among these hits are 11 predicted transmembrane proteins, including Stim, and one, olf186-F, that upon RNA interference-mediated knockdown exhibited a profound reduction of thapsigargin-evoked Ca(2+) entry and CRAC current, and upon overexpression a 3-fold augmentation of CRAC current [1].

References

Genome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activity. Zhang, S.L., Yeromin, A.V., Zhang, X.H., Yu, Y., Safrina, O., Penna, A., Roos, J., Stauderman, K.A., Cahalan, M.D. Proc. Natl. Acad. Sci. U.S.A. (2006) [Pubmed]

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