Gene Review:
mp42-a - mitotic phosphoprotein
Xenopus laevis
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High impact information on mp42-a
- Premature mitotic entry in the absence of Pin1 was accompanied by hyperphosphorylation of Cdc25, activation of Cdc2/cyclin B, and generation of epitopes recognized by the mitotic phosphoprotein antibody, MPM-2 [1].
References
- Requirement of the prolyl isomerase Pin1 for the replication checkpoint. Winkler, K.E., Swenson, K.I., Kornbluth, S., Means, A.R. Science (2000) [Pubmed]
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