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Gene Review

adam10  -  ADAM metallopeptidase domain 10

Xenopus laevis

Synonyms: ad10, cd156c, kuz, kuzbanian, madm, ...
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Disease relevance of ADAM10


High impact information on ADAM10

  • Using chimeric constructs, we find that the metalloprotease domain of ADAM10 can substitute for that of ADAM13, but that specificity for cement gland expansion requires a downstream extracellular domain of ADAM13 [1].


  1. The cysteine-rich domain regulates ADAM protease function in vivo. Smith, K.M., Gaultier, A., Cousin, H., Alfandari, D., White, J.M., DeSimone, D.W. J. Cell Biol. (2002) [Pubmed]
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