Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

BCAR4 - breast cancer anti-estrogen resistance 4...

Homo sapiens

Meijer, D. et al., Van Agthoven, T.

Ton Van Agthoven,

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Disease relevance of BCAR4

We showed that ectopic expression of this gene, designated as breast cancer antiestrogen resistance 4 (BCAR4), caused OH-TAM resistance and anchorage-independent cell growth in ZR-75-1 cells and that the intact open reading frame was required for its function [1].
[2]

References

Functional screen for genes responsible for tamoxifen resistance in human breast cancer cells. Meijer, D., van Agthoven, T., Bosma, P.T., Nooter, K., Dorssers, L.C. Mol. Cancer Res. (2006) [Pubmed]
Relevance of BCAR4 in tamoxifen resistance and tumour aggressiveness of human breast cancer. Godinho, M.F., Sieuwerts, A.M., Look, M.P., Meijer, D., Foekens, J.A., Dorssers, L.C., van Agthoven, T. Br. J. Cancer. (2010) [Pubmed]

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