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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Ly49i5  -  Ly49 inhibitory receptor 5

Rattus norvegicus

 
 
 
 
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High impact information on Ly49i5

  • Using a new mAb (mAb Fly5), we showed that Ly49i5 is an inhibitory receptor that recognizes ligands encoded within the class Ib region of the u and l haplotypes, while the structurally related Ly49s5 is an activating receptor that recognizes class Ib ligands of the u haplotype [1].

References

  1. Two structurally related rat Ly49 receptors with opposing functions (Ly49 stimulatory receptor 5 and Ly49 inhibitory receptor 5) recognize nonclassical MHC class Ib-encoded target ligands. Naper, C., Dai, K.Z., Kveberg, L., Rolstad, B., Niemi, E.C., Vaage, J.T., Ryan, J.C. J. Immunol. (2005) [Pubmed]
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