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Gene Review

MRPL2  -  mitochondrial ribosomal protein L2

Homo sapiens

Synonyms: 39S ribosomal protein L2, mitochondrial, CGI-22, L2mt, MRP-L14, MRP-L2, ...
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Disease relevance of MRPL2

  • In particular, this is shown for the mammalian counterparts of the E. coli EcoL2 ribosomal protein (MRP-L14), that do not conserve the specific and functional highly important His(229) residue of E. coli and the corresponding yeast mitochondrial Rml2p [1].


  1. Mammalian mitochondrial ribosomal proteins (2). Amino acid sequencing, characterization, and identification of corresponding gene sequences. O'Brien, T.W., Fiesler, S.E., Denslow, N.D., Thiede, B., Wittmann-Liebold, B., Mougey, E.B., Sylvester, J.E., Graack, H.R. J. Biol. Chem. (1999) [Pubmed]
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