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Gene Review

SNORD74  -  small nucleolar RNA, C/D box 74

Homo sapiens

Synonyms: U74, Z18
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High impact information on SNORD74

  • These studies revealed that several conserved snRNA regions are close to U(+10) in activated spliceosomes, namely (i) the U6 snRNA ACAGAG-box region, (ii) portions of the U6 intramolecular stem-loop (U6-ISL) including a nucleotide implicated in the first catalytic step (U74), and (iii) the region of U2 that interacts with the branch point [1].


  1. Proximity of conserved U6 and U2 snRNA elements to the 5' splice site region in activated spliceosomes. Rhode, B.M., Hartmuth, K., Westhof, E., Lührmann, R. EMBO J. (2006) [Pubmed]
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