Aliases:

MGC5576

MGC111210

Endoplasmic reticulum membrane protein overexpressed in cancer- EMOC  

Chromosome Location:

Chromosomal Locus: Chr  . 12q13.1

Transcript Variants:

Variant 1 isoform a: 250   aa and 1606   bps

Variant 2 isoform a: 250   aa and 1535   bps

Variant 3 isoform b: 231   aa and 1549   bps

Variant 4 isoform b: 231   aa and 1478   bps

Paralogs:

TMEM106A  

TMEM106B  

Orthologs:

Chimpanze  , Sumatran orangutan, Northern-white-cheeked gibbon, Marmoset, Dog, Pig, Giant panda, Horse, Cow, Elephant, House mouse, Brown rat, Green anole, African clawed-frog, Turkey, Chicken, Western clawed-frog, Zebra fish, Florida lancelet, Termatode, and Starlet sea anemone

Internal Protein Structure:

Two Transmembrane Regions

• Amino   acid 87...107
• Amino   acid 197...217

Domain of unknown function region

• DUF1356  

Internal Nucleotide Structure:

Two Transmembrane Regions

• Base   pair 445...507
• Base   pair 775...837

Coding Sequence

• Base   pair 187...939

Interesting Protein Information

• Tryptophan   Free
• Highly conserved through distant orthologs