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Sil1  -  endoplasmic reticulum chaperone SIL1...

Mus musculus

Synonyms: 1810057E01Rik, AI042831, Nucleotide exchange factor SIL1, wz
 
 
 
 
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High impact information on Sil1

  • We report that the wz mutation disrupts the gene Sil1 that encodes an adenine nucleotide exchange factor of BiP, a crucial ER chaperone [1].

References

  1. Protein accumulation and neurodegeneration in the woozy mutant mouse is caused by disruption of SIL1, a cochaperone of BiP. Zhao, L., Longo-Guess, C., Harris, B.S., Lee, J.W., Ackerman, S.L. Nat. Genet. (2005) [Pubmed]
 
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