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Gene Review

FAM126A  -  family with sequence similarity 126, member A

Homo sapiens

Synonyms: DRCTNNB1A, Down-regulated by CTNNB1 protein A, HCC, HLD5, HYCC1, ...
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Disease relevance of FAM126A

  • Furthermore, we documented reduced expression of DRCTNNB1A in 12 of 15 primary colorectal cancers examined, compared with corresponding adjacent noncancerous mucosae [1].

Analytical, diagnostic and therapeutic context of FAM126A

  • The transcript was expressed in all human tissues examined, and we assigned the genomic location of DRCTNNB1A to chromosomal band 7p15.3 by in situ hybridization [1].


  1. Isolation and characterization of a novel human gene, DRCTNNB1A, the expression of which is down-regulated by beta-catenin. Kawasoe, T., Furukawa, Y., Daigo, Y., Nishiwaki, T., Ishiguro, H., Fujita, M., Satoh, S., Miwa, N., Nagasawa, Y., Miyoshi, Y., Ogawa, M., Nakamura, Y. Cancer Res. (2000) [Pubmed]
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