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Gene Review

KDM2B  -  lysine (K)-specific demethylase 2B

Homo sapiens

Synonyms: CXXC-type zinc finger protein 2, CXXC2, F-box and leucine-rich repeat protein 10, F-box protein FBL10, F-box/LRR-repeat protein 10, ...
 
 
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High impact information on FBXL10

  • We show that BCOR coimmunoprecipitates isoforms of FBXL10 which contain a JmjC domain that recently has been determined to have histone H3K36 demethylase activity [1].
  • FBXL19 consists of FBXHA and FBXHB domains, while FBXL10 and FBXL11 consist of Jumonji C (JmjC), FBXHA and FBXHB domains [2].

References

  1. Polycomb group and SCF ubiquitin ligases are found in a novel BCOR complex that is recruited to BCL6 targets. Gearhart, M.D., Corcoran, C.M., Wamstad, J.A., Bardwell, V.J. Mol. Cell. Biol. (2006) [Pubmed]
  2. Identification and characterization of FBXL19 gene in silico. Katoh, M., Katoh, M. Int. J. Mol. Med. (2004) [Pubmed]
 
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