The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

RNH202  -  Rnh202p

Saccharomyces cerevisiae S288c

Synonyms: RNase H(202), RNase H2 subunit B, Ribonuclease H2 subunit B, Ribonuclease HI subunit B, Rnh2B, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on RNH202

  • Cells lacking RNH202 showed synthetic growth defects when combined with either mus81 or sgs1 alone [1].
  • But, whereas the loss of RAD51 had little effect on rnh202 sgs1 double mutants, it strongly inhibited the growth of rnh202 mus81 cells [1].
  • By affinity chromatography purification and identification of polypeptides associated with a tagged S.cerevisiae Rnh2Ap, we obtained a complex of three proteins [Rnh2Ap (Rnh201p), Ydr279p (Rnh202p) and Ylr154p (Rnh203p)] that together are necessary and sufficient for RNase H2 activity [correction] [2].


  1. Roles of SGS1, MUS81, and RAD51 in the repair of lagging-strand replication defects in Saccharomyces cerevisiae. Ii, M., Brill, S.J. Curr. Genet. (2005) [Pubmed]
  2. RNase H2 of Saccharomyces cerevisiae is a complex of three proteins. Jeong, H.S., Backlund, P.S., Chen, H.C., Karavanov, A.A., Crouch, R.J. Nucleic Acids Res. (2004) [Pubmed]
WikiGenes - Universities