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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

SYF1  -  Syf1p

Saccharomyces cerevisiae S288c

Synonyms: NTC90, PRP19-associated complex protein 90, Pre-mRNA-splicing factor SYF1, Synthetic lethal with CDC40 protein 1, YDR416W
 
 
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High impact information on SYF1

  • The other three, SYF1, SYF2, and SYF3, represent genes also involved in cell cycle progression and in pre-mRNA splicing [1].
  • Syf1p and Syf3p are highly conserved proteins containing several copies of a repeated motif, which we term RTPR [1].
  • We discuss the likelihood that Syf1p, Syf2p, and Syf3p are components of a protein complex that assembles into spliceosomes and also regulates cell cycle progression [2].

References

  1. Genetic and physical interactions between factors involved in both cell cycle progression and pre-mRNA splicing in Saccharomyces cerevisiae. Ben-Yehuda, S., Dix, I., Russell, C.S., McGarvey, M., Beggs, J.D., Kupiec, M. Genetics (2000) [Pubmed]
  2. Functional analyses of interacting factors involved in both pre-mRNA splicing and cell cycle progression in Saccharomyces cerevisiae. Russell, C.S., Ben-Yehuda, S., Dix, I., Kupiec, M., Beggs, J.D. RNA (2000) [Pubmed]
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