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Gene Review

RSM22  -  mitochondrial 37S ribosomal protein RSM22

Saccharomyces cerevisiae S288c

Synonyms: 37S ribosomal protein S22, mitochondrial, YKL155C, YKL610
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High impact information on RSM22

  • Fusion of the N terminus of Cox11 to the matrix ribosomal protein Rsm22 results in a functional protein capable of suppressing the respiratory defect of both Deltacox11 cells and Deltarsm22 cells [1].
  • One of these proteins (pre-Rsm22-Cox11) consists of a fusion of Rsm22, a component of the mitochondrial ribosome, and Cox11, a factor required for copper insertion into cytochrome oxidase [2].


  1. Functional analysis of the domains in Cox11. Carr, H.S., Maxfield, A.B., Horng, Y.C., Winge, D.R. J. Biol. Chem. (2005) [Pubmed]
  2. Sequential processing of a mitochondrial tandem protein: insights into protein import in Schizosaccharomyces pombe. Khalimonchuk, O., Ott, M., Funes, S., Ostermann, K., Rödel, G., Herrmann, J.M. Eukaryotic Cell (2006) [Pubmed]
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