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Gene Review

ZIC5  -  Zic family member 5

Homo sapiens

Synonyms: Zinc finger protein ZIC 5, Zinc finger protein of the cerebellum 5
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Disease relevance of ZIC5

  • The minimal deletion interval associated with the Dandy-Walker malformation (DWM) was narrowed to the 13q32.2-33.2 region, in which the ZIC2 and ZIC5 genes proposed as underlying various CNS malformations are mapped [1].


  1. 13q Deletion and central nervous system anomalies: further insights from karyotype-phenotype analyses of 14 patients. Ballarati, L., Rossi, E., Bonati, M.T., Gimelli, S., Maraschio, P., Finelli, P., Giglio, S., Lapi, E., Bedeschi, M.F., Guerneri, S., Arrigo, G., Patricelli, M.G., Mattina, T., Guzzardi, O., Pecile, V., Police, A., Scarano, G., Larizza, L., Zuffardi, O., Giardino, D. J. Med. Genet. (2007) [Pubmed]
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