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Gene Review:

SSB2 - Hsp70 family ATPase SSB2

Saccharomyces cerevisiae S288c

Synonyms: Heat shock protein SSB2, N1333, YNL209W

Jong, A.Y. et al., Boorstein, W.R. et al., Werner-Washburne, M. et al.

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High impact information on SSB2

SSB-1 stimulates purified yeast DNA polymerase I, while SSB-2 inhibits DNA polymerase I. An antibody against SSB-1 has been prepared in rabbits and purified by SSB-1-Sepharose affinity chromatography [1].
Here we present the nucleotide sequence of the SSA3 and SSB2 genes, completing the nucleotide sequence data for the yeast HSP70 family [2].

Biological context of SSB2

During growth to stationary phase, SSB1-SSB2 and SSC1 RNAs decreased in abundance as cell density increased [3].

References

Multiple species of single-stranded nucleic acid-binding proteins in Saccharomyces cerevisiae. Jong, A.Y., Aebersold, R., Campbell, J.L. J. Biol. Chem. (1985) [Pubmed]
Molecular evolution of the HSP70 multigene family. Boorstein, W.R., Ziegelhoffer, T., Craig, E.A. J. Mol. Evol. (1994) [Pubmed]
Yeast Hsp70 RNA levels vary in response to the physiological status of the cell. Werner-Washburne, M., Becker, J., Kosic-Smithers, J., Craig, E.A. J. Bacteriol. (1989) [Pubmed]

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AGOS_ABL174C	Ashbya gossypii ATCC 10895
KLLA0D19041g	Kluyveromyces lactis NRRL Y-1140
MGG_11513	Magnaporthe oryzae 70-15
NCU02075	Neurospora crassa OR74A
SSB1	Saccharomyces cerevisiae S288c
sks2	Schizosaccharomyces pombe 972h-

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