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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

UBP5  -  Ubp5p

Saccharomyces cerevisiae S288c

Synonyms: Deubiquitinating enzyme 5, Ubiquitin carboxyl-terminal hydrolase 5, Ubiquitin thioesterase 5, Ubiquitin-specific-processing protease 5, YER144C
 
 
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High impact information on UBP5

  • The K. lactis protein is 42% identical to Doa4, but unexpectedly the K. lactis gene is slightly closer in nucleotide sequence to UBP5, which cannot substitute for DOA4 even in high dosage [1].
  • However, disruption of the UBP5 gene in a haploid strain did not result in a noticeable phenotypic alteration [2].

References

  1. Analysis of the deubiquitinating enzymes of the yeast Saccharomyces cerevisiae. Amerik, A.Y., Li, S.J., Hochstrasser, M. Biol. Chem. (2000) [Pubmed]
  2. UBP5 encodes a putative yeast ubiquitin-specific protease that is related to the human Tre-2 oncogene product. Xiao, W., Fontanie, T., Tang, M. Yeast (1994) [Pubmed]
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