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Gene Review

ZNF276  -  zinc finger protein 276

Homo sapiens

Synonyms: CENP-Z, CENPZ, MGC45417, ZADT, ZFP276, ...
 
 
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Disease relevance of ZNF276

 

High impact information on ZNF276

  • The overlapping genomic organization between Zfp276 and Fanca may have relevance to the disease phenotype of FA [2].
  • Interestingly, Zfp276 is situated in the Fanca locus, and the 3'UTR of its cDNA overlaps with the last four exons of Fanca in a tail-to-tail manner [2].

References

  1. Cloning and mutation analysis of ZFP276 as a candidate tumor suppressor in breast cancer. Wong, J.C., Gokgoz, N., Alon, N., Andrulis, I.L., Buchwald, M. J. Hum. Genet. (2003) [Pubmed]
  2. Cloning and analysis of the mouse Fanconi anemia group A cDNA and an overlapping penta zinc finger cDNA. Wong, J.C., Alon, N., Norga, K., Kruyt, F.A., Youssoufian, H., Buchwald, M. Genomics (2000) [Pubmed]
 
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