Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

alaS - alanyl-tRNA synthetase

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK2692, JW2667, act, ala-act, lovB

Theall, G. et al., Miller, W.T. et al.

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Disease relevance of alaS

Escherichia coli alanyl-tRNA synthetase contains the sequence Cys-X2-Cys-X6-His-X2-His [1].

High impact information on alaS

Suppression of a defective alanyl-tRNA synthetase in Escherichia coli: a compensatory mutation to high alanine affinity [2].

References

Evidence for a "cysteine-histidine box" metal-binding site in an Escherichia coli aminoacyl-tRNA synthetase. Miller, W.T., Hill, K.A., Schimmel, P. Biochemistry (1991) [Pubmed]
Suppression of a defective alanyl-tRNA synthetase in Escherichia coli: a compensatory mutation to high alanine affinity. Theall, G., Low, K.B., Söll, D. Mol. Gen. Genet. (1977) [Pubmed]

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