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Gene Review

THEMIS2  -  thymocyte selection associated family...

Homo sapiens

Synonyms: C1orf38, ICB-1, ICB1, Icb-1, Induced by contact to basement membrane 1 protein, ...

Disease relevance of C1orf38


Other information

[2][3][4] [5] [6] [7] [8]


  1. A novel basement membrane-induced gene identified in the human endometrial adenocarcinoma cell line HEC1B. Treeck, O., Strunck, E., Vollmer, G. FEBS. Lett. (1998) [Pubmed]
  2. icb-1 Gene counteracts growth of ovarian cancer cell lines. Treeck, O., Schüler, S., Häring, J., Skrzypczak, M., Lattrich, C., Ortmann, O. Cancer. Lett. (2013) [Pubmed]
  3. Icb-1 gene polymorphism rs1467465 is associated with susceptibility to ovarian cancer. Schüler, S., Lattrich, C., Skrzypczak, M., Fehm, T., Ortmann, O., Treeck, O. J. Ovarian. Res. (2014) [Pubmed]
  4. Network analysis of icb-1 gene function in human breast cancer cells. Treeck, O., Belgutay, D., Häring, J., Schüler, S., Lattrich, C., Ortmann, O. J. Cell. Biochem. (2012) [Pubmed]
  5. Knockdown of ICB-1 gene enhanced estrogen responsiveness of ovarian and breast cancer cells. Konwisorz, A., Springwald, A., Haselberger, M., Goerse, R., Ortmann, O., Treeck, O. Endocr. Relat. Cancer. (2010) [Pubmed]
  6. Single nucleotide polymorphisms in human gene icb-1 and breast cancer susceptibility. Springwald, A., Lattrich, C., Seitz, S., Ortmann, O., Treeck, O. Cancer. Invest. (2009) [Pubmed]
  7. Expression of differentiation-associated gene icb-1 is estrogen-responsive in ovarian and breast cancer cell lines. Bollmann, J., Ortmann, O., Treeck, O. J. Steroid. Biochem. Mol. Biol. (2008) [Pubmed]
  8. Detection of increased icb-1 transcript levels in maturing HL-60 cells: a novel marker for granulocytic and monocytic in vitro differentiation. Treeck, O., Odani, T., Itoh, N., Imai, H., Fujita, S., Kohroki, J., Nakanishi, T., Diedrich, K., Ortmann, O., Tanaka, K., Vollmer, G. Leuk. Res. (2002) [Pubmed]
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