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Gene Review:

selB - selenocysteinyl-tRNA-specific translation...

Escherichia coli O157:H7 str. EDL933

Gr??be, T. et al., Li, C. et al.

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Disease relevance of selB

GrdB could be heterologously produced in Escherichia coli with coexpression of selB and selC from E. acidaminophilum for selenocysteine insertion [1].

High impact information on selB

All the selB suppressor mutations isolated were clustered in a region corresponding to 28 amino acids in the SelB C-terminal subdomain 4b [2].

References

Peroxidase activity of selenoprotein GrdB of glycine reductase and stabilisation of its integrity by components of proprotein GrdE from Eubacterium acidaminophilum. Gr??be, T., Reuter, M., Gursinsky, T., S??hling, B., Andreesen, J.R. Arch. Microbiol. (2007) [Pubmed]
The bulged nucleotide in the Escherichia coli minimal selenocysteine insertion sequence participates in interaction with SelB: a genetic approach. Li, C., Reches, M., Engelberg-Kulka, H. J. Bacteriol. (2000) [Pubmed]

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