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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

URB1  -  URB1 ribosome biogenesis 1 homolog (S....

Homo sapiens

Synonyms: C21orf108, KIAA0539, NOP254, NPA1, Nucleolar pre-ribosomal-associated protein 1, ...
 
 
 
 
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High impact information on URB1

  • In the absence of Npa1p, the pre-rRNA processing pathway leading to 5.8S and 25S rRNA production is perturbed such that the C2 cleavage within internal transcribed spacer 2 occurs prematurely [1].

References

  1. Npa1p, a component of very early pre-60S ribosomal particles, associates with a subset of small nucleolar RNPs required for peptidyl transferase center modification. Dez, C., Froment, C., Noaillac-Depeyre, J., Monsarrat, B., Caizergues-Ferrer, M., Henry, Y. Mol. Cell. Biol. (2004) [Pubmed]
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