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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Metabolism of liriodendrin and syringin by human intestinal bacteria and their relation to in vitro cytotoxicity.

When liriodendrin or syringin was incubated for 24 h with human intestinal bacteria, two metabolites, (+)-syringaresinol-beta-D-glucopyranoside and (+)-syringaresinol, from liriodendrin and one metabolite, synapyl alcohol, from syringin were produced. The metabolic time course of liriodendrin was as follows: at early time, liriodendrin was converted to (+)-syringaresinol-beta-D-glucopyranoside, and then (+)-syringaresinol. The in vitro cytotoxicities of these metabolites, (+)-syringaresinol and synapyl alcohol, were superior to those of liriodendrin and syringin.[1]

References

  1. Metabolism of liriodendrin and syringin by human intestinal bacteria and their relation to in vitro cytotoxicity. Kim, D.H., Lee, K.T., Bae, E.A., Han, M.J., Park, H.J. Arch. Pharm. Res. (1999) [Pubmed]
 
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