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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Various applications of liquid chromatography-mass spectrometry to the analysis of phenolic compounds.

Different options of liquid chromatography-mass spectrometry were used to establish the most suitable ion source and conditions to analyse or detect some low-molecular mass phenols, flavan-3-ols, and apply such conditions to a complex sample (wine). Data presented in this work confirm the great utility of atmospheric pressure-ionisation electrospray mass spectrometry coupled to HPLC for analysis of phenolic compounds, under negative mode in the case of low-molecular mass phenols, and under both positive and negative modes in flavan-3-ol compounds. A fragmentor voltage of 60 V could be the most suitable for analysing the compounds under study.[1]

References

  1. Various applications of liquid chromatography-mass spectrometry to the analysis of phenolic compounds. Pérez-Magariño, S., Revilla, I., González-SanJosé, M.L., Beltrán, S. Journal of chromatography. A. (1999) [Pubmed]
 
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